betaIG-H3 protein

binds to type I, II, and IV collagens; may play an important role in cell-collagen interactions; in cartilage, may be involved in endochondral bone formation; the gene was induced in a human adenocarcinoma cell line after treatment with TGF-beta; defects in TGGBI causes CORNEAL DYSTROPHIES, HEREDITARY; amino acid sequence in first source; RefSeq NM_009369 (mouse), NM_000358 (human); GenBank AB086407 (Zebrafish)

Also Known As:

keratoepithelin; BIGH3 protein; BIGH3 protein, human; Beta ig-h3 protein, zebrafish; Beta-ig protein, mouse; RGD-CAP protein; RGD-CAP protein, human; RGD-containing collagen associated protein; RGD-containing collagen associated protein, human; TGFBI protein; TGFBI protein, human; TGFBIp protein; Tgfbi protein, mouse; beta IG-H3 protein; big-h3 protein, mouse; bigh3 protein, zebrafish; kerato-epithelin; kerato-epithelin protein, human; kerato-epithilin; tgfbi protein, zebrafish; transforming growth factor, beta induced protein, mouse; transforming growth factor, beta-induced, 68kDa protein, human; transforming growth factor-beta induced protein

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Transforming Growth Factor beta: 14070
        betaIG-H3 protein: 110
    - TGF-beta Superfamily Proteins: 1
      - Transforming Growth Factor beta: 14070
        betaIG-H3 protein: 110
  - Scleroproteins: 75
    - Extracellular Matrix Proteins: 3213
      - betaIG-H3 protein: 110
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Transforming Growth Factor beta: 14070
        betaIG-H3 protein: 110
    - TGF-beta Superfamily Proteins: 1
      - Transforming Growth Factor beta: 14070
        betaIG-H3 protein: 110
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Transforming Growth Factor beta: 14070
      - betaIG-H3 protein: 110
  - TGF-beta Superfamily Proteins: 1
    - Transforming Growth Factor beta: 14070
      - betaIG-H3 protein: 110

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Disease

Drug/Important Bio-Agent (IBA)